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The authors noted that results from more recent studies were less positive than those from earlier studies, and concluded that routine clinical use of ALCAR to treat dementia signs and symptoms was not justified [15]

The evidence base for B12 supplementation is stronger than for L-carnitine in the context of GLP-1 medications, at least in terms of addressing a documented risk (B12 deficiency during prolonged GLP-1 use)

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Clinician's Guide to the Management of Mitochondrial Disease: A Manual for Primary Care Providers