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Reduced insulin-mediated citrate synthase activity in cultured skeletal muscle cells from patients with type 2 diabetes: evidence for an intrinsic oxidative enzyme defect

Rare risks include copper toxicity, particularly in individuals with underlying conditions such as Wilsons disease (a genetic disorder causing copper accumulation), and theoretical concerns regarding angiogenesis promotion in the context of active cancers

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doi: 10.1161/HYPERTENSIONAHA.120.16667 [DOI] [PMC free article] [PubMed] [Google Scholar] 157.Effects of enalapril on mortality in severe congestive heart failure

Common in obesity and metabolic syndrome