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Malabsorption (insufficient intake of vitamin B12in the intestine) due to insufficient production of intrinsic factor (a protein that is formed in the gastric mucosa and is required for the absorption of vitamin B12), Diseases in the end section of the ileum (part of the small intestine), e.g

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Ultra-B12 Injection is used in the treatment of Nutritional deficiencies

Choline aids in the emulsification of fat and cholesterol