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Finlin, B

Declarations Ethics approval and consent to participate Not applicable

They are most effective when combined with balanced nutrition, consistent exercise, and professional supervision

Association between weight reduction achieved with tirzepatide and health-related quality of life in people with overweight or obesity

Some individuals may experience: Increased heart rate Jitteriness or anxiety Sleep disruption Energy crashes Caffeine dependency over time People who are sensitive to stimulants or who train later in the evening may prefer stimulant-free supplementation options

Adjusted mean AC levels across the three groups were estimated from the mixed models, standardized differences between groups were reported using Cohens d tested in post-hoc pairwise comparisons