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[DOI] [PMC free article] [PubMed] [Google Scholar] Kang KA, Piao MJ, Ryu YS, Hyun YJ, Park JE, Shilnikova K, Zhen AX, Kang HK, Koh YS, Jeong YJ, Hyun JW

Elevated homocysteine levels can inhibit the activity of MS enzyme, leading to decreased SAMe production

Whereas, further rise in the ROS level is accompanied with down regulation of cellular antioxidant defense systems in tumor malignancy through various molecular targets including nuclear factor kappa-light-chain-enhancer of activated B cells (NF-B) and nuclear respiratory factor 2 (Nrf2) [6, 7]
NeuroReport 7:18331836 Raps SP, Lai JC, Hertz L, Cooper AJ (1989) Glutathione is present in high concentrations in cultured astrocytes but not in cultured neurons

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Gruber A, Horwood F, Sithole J, Ali NJ, Idris I
