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Melanocytic nevi are derived from melanocytes or their precursors, and distinguish themselves by virtue of (1) the absence of dendrites

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Note that animals which are recumbent (downer cows or post-surgical patients) will have high CK activity (up to 10 x normal) from muscle injury or ischemia

Functioning as a potent exercise mimetic, this small-molecule compound enhances mitochondrial function, fatty acid oxidation, and oxidative muscle fiber composition, thereby improving exercise endurance, cardiac metabolic efficiency, and systemic energy expenditure without increasing food intake 1-4