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Bridging the Gap: Expanding Access to Minimally Invasive Thoracic Surgery to Reduce Health Disparities

Seminars in Liver Disease, 39(02), 221234

Drug Metabolism COPING WITH EXPOSURE TO XENOBIOTICS Substances foreign to the body, or xenobiotics , are metabolized by the same enzymatic pathways and transport systems that are used for normal metabolism of dietary constituents

Most tick-borne diseases, including Lyme, are caused by bacteria spread by a tick bite

In normal cells, P-glycoprotein, MRP1, ABCG2, and several other clinically relevant MRP-related drug transporters are often expressed in a polarized manner and contribute to drug absorption (bioavailability), distribution (limiting drug access to so-called pharmacological sanctuaries such as the brain, cerebral spinal fluid, and testes), and elimination (efflux into bile or urine) (Fig
