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The JAK/STAT signaling pathway: from bench to clinic

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Importantly, the expression of these genes is controlled by the transcription factor NRF2, and, in fact, the level of this protein was highly reduced in the most sensitive cell line, NCI H23, explaining the reduced expression of genes involved in GSH synthesis (Fig

However, it is important to keep in mind that MAOA more strongly affects dopamine levels in rodents than in humans

Lahiri, N

issues with sensitivity due to kinetic discrepancies (e.g., confounding stoichiometry in ORAC resulting from area-under-the-curve integration) and inherent probe limitations (e.g., the pH dependency of fluorescein)