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Increased expression of factors associated with complement activation such as C1q, C3, C5, and MAC are present in both glaucomatous patients and experimental animal models of glaucoma, noting that this increase occurs very early in response to IOP elevation (Stasi et al., 2006

It is primarily found in the liver, where it plays a vital role in detoxifying harmful substances, supporting immune function, and maintaining cellular health

Therefore, it is not the dosage that plays the decisive role, but the complexity of the composition of the vitamin additives

These conditions are also typified by loss of mitochondrial health through dysfunction of homeostatic components such as mitophagy, unfolded protein response, and the antioxidant system

10.1111/j.1464-410X.2006.06525.x BJU Int