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Neurosci Lett 687:104110 Jensen FE et al (1994) The putative essential nutrient Pyrroloquinoline quinone is neuroprotective in a rodent model of hypoxic/ischemic brain injury

While some of her patients report noticing performance improvement benefits, Sogol Ash says theres still a need for large-scale human studies

Let vial sit for 2-3 minutes

For example, individuals with certain medical conditions, such as kidney disease or certain blood disorders, may need to exercise caution or avoid B12 shots altogether

1178-1188 5) Houston JB (1994) Utility of in vitro drug metabolism data in predicting in vivo metabolic clearance Biochem Pharmacol 47(9)

So the research exists, but the public awareness doesnt