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This explicit requirement for lipid peroxidation is a core feature of ferroptosis that distinguishes it from other forms of cell death: ferroptosis inhibitors cannot prevent other forms of cell death (Yang et al., 2014), and conversely classic inhibitors of necrosis, apoptosis, and autophagy do not modulate ferroptosis ( Figure 1 )

Why the Body Relies on Glutathione Every metabolic process that generates energy also generates oxidative byproducts

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