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A few, like KPV, have an anti-inflammatory rationale extrapolated from preclinical research, but that is experimental, not proven

Gastroenterology 144 , 369380 (2013)

Vitamin B12 and the Elderly Unfortunately, vitamin B12 absorption in the body naturally decreases as we age

C.WongS

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Lynda Scammell, the head of borderline products at the MHRA, said: Where medicinal claims are made, or products are being used in a way which brings them within the definition of a medicinal product under the Human Medicines Regulations 2012, a peptide-containing product must hold a marketing authorisation to be legally sold or supplied in the UK