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doi: 10.1038/s41568-020-00329-7 [DOI] [PubMed] [Google Scholar] 118.Wang X, Chen Q, Zhang X, et al

The cumulative effect of months of treatment becomes clearly visible
Some practitioners run continuous protocols, but cycling remains the conservative approach until more long-term data exists

in press [DOI] [PubMed] 13.Park EY, Shimura N, Konishi T, Sauchi Y, Wada S, Aoi W, et al

Hyperimmunoglobulin D syndrome (HIDS), a monogenic autoinflammatory disorder, features erythematous rashes and recurrent sterile inflammation

That is the evidence gap in one sentence
