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Br J Pharmacol 121(5):889900 Colado MI, OShea E, Esteban B, Granados R, Green AR (1999) In vivo evidence against clomethiazole being neuroprotective against MDMA (ecstasy)-induced degeneration of rat brain 5-HT nerve terminals by a free radical scavenging mechanism

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Beyond these established factors, emerging evidence suggests that the disruption of copper homeostasis and the induction of cuproptosis are critical integrative mechanisms that potentially link systemic inflammatory-metabolic stress to direct cardiomyocyte death [174]

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Johnson seems reasonably confident that it can happen in our lifetimes which is why he is so keen to stick around for it
