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Key regulators such as AKR1B1 (aldose reductase isoform), GSK-3 (glycogen synthase kinase 3), TNF-, and IFN- are central to the inflammatory and metabolic dysregulation seen in this condition, yet their modulation by HS has not gained traction

& Imataka, H

ICH for pharmaceuticals, Plant Protection Products Regulation) foresee that the in vitro testing battery is always followed up by in vivo testing

Because the feeble mutation suppressed SLE in mice, [53] the SLC15A4 protein has become a target of interest for drug development

doi: 10.7759/cureus.51655, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] Troshneva A

Collectively, these findings support the therapeutic potential of targeting Mirk kinase to overcome chemoresistance in ovarian cancer, particularly by eliminating quiescent tumour cells