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The reason this form of carnitine is used as a nootropic is that ALCAR more readily crosses the blood-brain barrier than other forms of L-carnitine supplements due to the addition of an acetyl group (-COCH3)

Sources: Alzheimer's Disease Study Multicenter, randomized, double-blind, placebo-controlled clinical trial for the efficacy of acetyl-L-carnitine in Alzheimer's disease

l-Carnitine, a nutrient found primarily in red meat, was recently reported to be metabolized by gut microbiota to form TMA via the 2-component Rieske-type l-carnitine oxygenase CntA/B (25, 26), which requires molecular oxygen for activity

Many individuals with cognitive impairment experience emotional challenges, such as depression or irritability

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