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In one randomized controlled trial, valacyclovir led to complete pain resolution sooner than acyclovir (44 versus 51 days) and required less frequent dosing

Afterward, wells were washed once with cold PBS (4 C) to remove unattached viral particles, and serum-free medium was added with or without (negative controls) 100 g/mL of peptides (KP or SP)

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Similar to the HIV gp120 protein, experimental data showed that as the thiol content in SARS-CoV S1 (the receptor-binding subunit) increased, its ability to bind to target cells decreased, suggesting that both viruses require a specific thiol content for fusion and entry to occur [37]