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In parallel, in vitro proof-of-concept experiments were conducted to elucidate putative mechanism of action of this formulation, focusing on wound healing and cytokine modulation under basal, inflammatory, and oxidative conditions

Antioxidants The human organism has developed specific and complex antioxidant mechanisms (enzymatic and non-enzymatic) which may act synergistically to protect cells and organs against RON damage

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ii) SOH intermediates: Protein sulfenic acid (P-SOH) reacts with GSH or GSNO (GSH-SOH)

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U2OS cells with stably overexpressing Flag-GCLC were treated with TBH or H 2 O 2