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doi: 10.3389/fcvm.2025.1636090 Received 27 May 2025 Revised 29 November 2025 Accepted 15 December 2025 Published 06 January 2026 Volume 12 - 2025 Edited by Xiaofeng Yang, Temple University, Philadelphia, United States Reviewed by Dotan Shaniv, Kaplan Medical Center, Israel Chongzhuang Tang, XenoFinder Co LTD, China Updates Copyright 2026 Li, Qu, Li and Li

It is created by specialized cells in the skin known as melanocytes

Reduces Inflammation & Oxidative Stress: GHK-Cu neutralizes harmful free radicals and reduces chronic inflammation, protecting the skin and body from premature aging

In turn, reduced Trx participates in the reduction of peroxiredoxins, which, together with GSH, form the main antioxidants of the red blood cell [RBC

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It works by preventing the infiltration of tyrosinase in order to achieve the purpose of inhibiting melanin formation
