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For example, guanine oxidation produces 8-oxo guanine (8-oxoG), which may lead to G-T or G-A transversions if unrepaired

[DOI] [PubMed] [Google Scholar] 152.Smedley PL, Kinniburgh DG

Singh R, Letai A, Sarosiek K
& Cecchini, A

Guidance for industry: diabetes mellitus evaluating cardiovascular risk in new antidiabetic therapies to treat type 2 diabetes

So, treating them is necessary to get back the rejuvenated look
