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While in vitro equilibrations between redox couples such as roGFP2 and GSH/GSSG require minutes or even hours to reach a thermodynamic endpoint (G = 0), enzyme-catalyzed thiol-disulfide exchange reactions usually occur very rapidly and either maintain or reach a steady state (G 0) 7,31,32,60,63,67,78,79

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Lymphocyte proliferation and immune responses require vast metabolic resources, especially thiols such as cysteine and glutathione

Inducible nitric oxide synthase gene expression in vascular cells after transient focal cerebral ischemia