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Namely, the irreversible monoamine oxidase (MAO B) inhibition (i.e., pargyline) and subsequent serotonin substrate (L-tryptophan as a serotonin precursor) induced fore paw treading, hind limbs abduction, wet dog shake, and hypothermia followed by hyperthermia in rats, which commonly occur in serotonin syndrome [66]

2026 Mar 22;27(6):2876

These findings were confirmed in primary hepatocytes taken from mice lacking MPC2 in the liver ( Mpc2 LKO ), when compared to cells from mice with an intact allele ( Mpc2 fl/fl )

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