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This process, known as non-enzymatic lipid peroxidation, is further fueled by Fe 2+ -dependent fenton reactions, which convert hydrogen peroxide (H 2 O 2 ) to OH and oxidize L-OOH by cleaving its O-O bond to generate LO and hydroxide ions (OH )

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This is where the compound's origin story and mechanism align most directly

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Retroviruses, 2015, 31, 64-70.Mbr C Lassiter, X Fan, PC Joshi, BA Jacob, RL Sutliff, DP Jones, M Koval and DM Guidot, HIV-1 transgene expression in rats causes oxidant stress and alveolar epithelial barrier dysfunction, AIDS Res