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[DOI] [PubMed] [Google Scholar] 212.Nieuwdorp M, Mooij HL, Kroon J, Atasever B, Spaan JA, Ince C, Holleman F, Diamant M, Heine RJ, Hoekstra JB, Kastelein JJ, Stroes ES, and Vink H

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This strategy effectively addresses the pharmacokinetic limitations of pGLP-2 while preserving its biological activity, offering a blueprint for the broader application of PEGylation in enhancing the stability and efficacy of therapeutic peptides vulnerable to enzymatic degradation

7e) and adds another layer that explains the lack of humoral response upon in vivo immunizations