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Intraoperative total spinal anesthesia as a complication of posterior percutaneous endoscopic cervical discectomy

Yes, severe untreated vitamin B12 deficiency can become dangerous over time

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Common underlying conditions include rheumatoid arthritis, inflammatory bowel disease, chronic infections, and cancer when the anemia is disease-related rather than chemotherapy-related

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Any references to biochemical pathways, receptor interactions, or enzymatic processes are provided solely for informational and research-context purposes