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-lipoic acid, acetylcysteine and -tocopherol) [27-29], -linolenic acid-containing oils [30] or acetyl-L-carnitine [31] have also been shown to produce some benefits on nerve function and even morphology in experimental diabetic models

These values are less than those reported in patients with growth hormone deficiency treated with 0.24 mg/kg/week

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In addition to various barriers that restrict the entry of several substances across the brain, some other provisions are present in the highly selective semipermeable membrane which help the transport of necessary materials in the brain, like the polar or hydrophilic components via the paracellular pathway, whereas small lipophilic substances are carried through transcellular pathway [157]

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