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Acylcarnitines produced as products of incomplete mitochondrial fatty acid oxidation have been detected in obesity, type 2 diabetes, cardiovascular disease, encephalopathy, and diseases of the eye, while patients with peroxisomal biogenesis disorders, such as Zellweger syndrome or X-linked adrenoleukodystrophy, or with acidemias have abnormal profiles of circulating acylcarnitines

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L-carnitine enables fatty acid transport into mitochondria, where beta-oxidation occurs the process of burning fat for fuel

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[DOI] [PMC free article] [PubMed] [Google Scholar] 77.van der Veen JN, Kennelly JP, Wan S, Vance JE, Vance DE, Jacobs RL

Furthermore, 2 g/d of L-carnitine L-tartrate (LCLT) supplementation for 3 wk attenuated exercise-induced plasma markers of purine catabolism and circulating cytosolic proteins 12