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GSH functions as an enzyme cofactor for Grxs, which are low-molecular-weight redox enzymes that are also known as thiol transferase, to maintain cellular redox homeostasis, and also acts as the primary reductant of the disulfide bonds of oxidized proteins [15] (Figure 1)

To access the CNS, HIV virus particles and the infected cells induce the BBB disruption

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HRMS (ESI) m/z Calcd for [M + H]+ 277.1036, found 277.1041.1H NMR (300 MHz, D2O): H (ppm) 1.992.08 (m, 4H), 2.302.41 (m, 2H), 2.392.47 (m, 2H), 3.673.73 (t, 2H, 2xCH)