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To limit a possible impact of N supply on vine vigor, the fertilization was fractionated into two doses for the soil N100 treatment and it was applied late in the season (at budbreak and at bloom)

Using a cut-off of 210.53 U/L, we achieved 75% sensitivity and 82% specificity

Nutritional immunity beyond iron: a role for manganese and zinc

A randomized, placebo-controlled trial in 559 elderly individuals with low serum levels of folate and vitamin B 12 and at increased risk of fracture evaluated the combined supplementation of very high doses of folic acid (5 mg/day) and vitamin B 12 (1.5 mg/day)

While animal studies have shown promising results, human clinical trials remain limited, which is precisely why recategorization and the research it enables are so important