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OP stimulates glutamine synthetase activity in peripheral organs [73]
doi: 10.1007/s11606-020-06008-5

Aprepitant Aprepitant as abortive therapy is recommended in patients that do not respond to standard treatment (sumatriptan and ondansetron) and in patients that have a defined prodrome or predictable periodicity (an episode that is related to the menstrual cycle)

Additional objectives were to further assess the safety of VPA in children with SMA, to assess performance of selected outcome measures for use in a multi-center clinical trials setting and to look for evidence that would support a biologic effect of VPA in these subjects, such as changes in SMN expression, electrophysiologic outcomes, or both

Reprod., 3, 19, 2006

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