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Regarding changes in the metabolome during milk gland involution, as determined by 1 H-NMR, we showed that acids increased, while organic acids, lipid metabolites, and carbohydrates and their derivatives decreased (Osthoff et al., 2026)

Front Endocrinol (Lausanne) (2022) 13:825934

Additionally, pathological TDP-43 aggregation is a hallmark of several neurodegenerative diseases, including frontotemporal lobar degeneration (FTLD) and ALS [164]

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For instance, Ekdahl and colleagues found that administration of minocycline, an anti-inflammatory drug, restored neurogenesis in the hippocampus and reduced activated microglia [99]

& Shao, J