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Cu ions can induce toxicity in mice if dosage exceeds levels of 35 mg/kg [26]

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The literature has disclosed that AFs altered the accumulation of lipids droplets and lipoproteins in addition to the dysregulation of lipid metabolism-related genes ( CHO, TAG, PHOL, MDA, Lipc, Lcat, Scarb1 , etc.) (223, 224)

27 Mammalian complex I contains 44 subunits, seven of which (ND1, ND2, ND3, ND4, ND4L, ND5 and ND6) are coded by the mitochondrial genome, and the others by the nuclear genome