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After release, TML is hydroxylated into 3-hydroxyl-6-N-trimethyl-lysine (HTML) by trimethyl dioxygenase (TMLD), which is then broken down into 4-N-trimethyl-butylaldehyde (TMABA) and glycine by HTML aldolase (HTMLA) (1)

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Like ubiquitination and sumoylation, neddylation is catalyzed by the enzyme cascade, namely, NEDD8 activating enzyme (E1), NEDD8 conjugating enzyme (E2), and NEDD8 ligase (E3)

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Active Ingredient: Acetyl-L-Carnitine 100mg/ml L-Carnitine is an amino acid supplement that may help to enhance energy production and also helps transport fats to muscle cells