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Key publications include Sikiric et al
The SURPASS clinical trial program demonstrated that tirzepatide at its highest dose (15 mg weekly) produced average weight loss of 20-25% of body weight, significantly exceeding the results seen with GLP-1 only agonists
Cautious use of parenteral cyanocobalamin is also recommended in patients with renal impairment, including premature neonates, because of the possibility of greater aluminum accumulation, which may cause central nervous system and bone toxicity
Sequence:H-Aib-His-D-2Nal-D-Phe-Lys-NH2
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