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An increased number of karyopyknotic cells was found in all four regions: cerebral and cerebellar cortex, hippocampus cortex, and hypothalamus/thalamus in control rats (Figure 8 and Figure 9)
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A large study of 2,000 obese adults found that participants using semaglutide combined with diet and exercise lost up to 15-20% of their body weight after 68 weeks
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