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10.1016/j.cmet.2023.12.027 71

Statistical analyses Pharmacokinetic and statistical analyses were performed using GraphPad Prism Version 9

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Neither group responded to naloxone when given prior to ALC administration, however, the low LH group responded nicely with an increase in LH (normal response) after the 16 weeks (with a three-fold higher max LH pulse and overall 8-fold increase in amount of LH secreted)