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Research on Flammulina velutipes fruiting bodies examined the impact of refrigeration on nutritional content and active ingredients, revealing a significant decline in the natural antioxidant L-ergothioneine concentration after 8 days at 5C in both bright and dark conditions, while total phenolic content increased notably over 10 days of refrigeration under fluorescent lighting
Several of the substances are slated for review by the Pharmacy Compounding Advisory Committee (PCAC), with meetings scheduled as early as July 2026

doi: 10.31083/j.jin2303064

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Research doesn't clearly favor one approach
