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Liu X, Yang J, Yuan Y, He Q, Gao Y, Jiang C, et al

The polarization of M1 macrophages is generally triggered by the synergistic action of inflammatory cytokines, such as IFN- and TNF, along with Toll-like receptors (TLRs) [94]

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These findings suggest that breathwork reduces oxidative stress by promoting the activity of endogenous antioxidant enzymes

It directly inhibits folate metabolism and indirectly disrupts associated pathways, including purine and pyrimidine synthesis

Jou I, Lee JH, Park SY, Yoon HJ, Joe EH, Park EJ (2006) Gangliosides trigger inflammatory responses via TLR4 in brain glia