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2.13 Mass spectrometry 2.13.1 Hydrogen-deuterium exchange mass spectrometry (HDX-MS) Time-resolved spontaneous hydrogen-deuterium exchange (HDX) of covalently bonded hydrogens of a protein with deuterium in solution provides information about protein conformation, flexibility, and solvent accessibility (Englander et al., 2016)

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doi: 10.4103/0304-4920.365459 215 SaxbyHMikropoulosCBoussiosS