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A recent study confirmed that among 1201 patients with NSCLC, more than 60% of initial responders to PD-L1 blockade relapse, and adaptive resistance to PD-L1 blockade in NSCLC is associated with ongoing but altered inflammation and IFN signaling [83]
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[PubMed: 11133160] 80
The lipid content of hepatocytes is regulated by the integrated activities of cellular enzymes that catalyse lipid uptake, synthesis, oxidation and export
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