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Future trials should also measure important outcomes such as the clinical signs and symptoms of vitamin B 12 deficiency, health related-quality of life, socioeconomic effects, and report adverse events adequately, preferably in a primary care setting. Clinical practice guidelines British Columbia Medical Services Commission (MSC)

doi: 10.1111/ijd.13585

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Most gut peptide research has been conducted in rodent models, and while the mechanistic data is compelling, translation to human outcomes has not been established through large clinical trials