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doi: 10.1002/(SICI)1098-1136(199606)17:2 3.0.CO;2-7

Ultrastructural analysis in retinal ganglion cells

This initiation dose establishes baseline receptor activation

Importantly, the research group which developed GPNMB vaccines also reported that GPNMB is an important regulator of lysosomal activity, and that genetic depletion of GPNMB can lead to shortened replicative lifespan in vascular endothelial cells, vascular dysfunction and increased formation of atherosclerotic plaques, with its effect on other tissues and organs remaining unclear

2), dass sie erst innerhalb der Zellen aktiv wird

After Week 6, a nonfixed dose tapering was started upon achieving response