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Common regimens use microgram (mcg) ranges, daily to weekly schedules, and cycles of 4 to 12 weeks before reassessment

International Journal of Womens Health , 13, 1121-1130

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This supports the notion that plasma Hcy is a more specific marker for overall functional folate status and indicates that baseline Hcy might be useful in predicting toxicity during pemetrexed therapy or be used as support for increased supplementation (either duration or dose) in individuals in whom Hcy remains elevated after initial supplementation

While it must be converted by the body into active coenzyme forms, its unique molecular structure makes it incredibly valuable in its own right
