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This dual capability positions melatonin as a robust non-enzymatic antioxidant, functioning both intra- and extracellularly [93]

It is a tightly regulated reaction that depends on both the availability of the amino acids (cysteine, glycine, and glutamate) and the rate-limiting enzyme, glutamate-cysteine ligase ( GCL )

Moreover, Makabe et al

LeBaron et al., 2023)

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