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At a median follow-up of 20.7 months, the addition of isatuximab to Kd yielded a statistically significant improvement in PFS (HR, 0.531

A recent study conducted on mice models of PD established that the N-homocysteinylation of -SN enhances its aggregation potential and increases its neurotoxicity and that higher Hcy levels correlated with more severe -synuclein deposition within mouse brains (Zhou et al