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For example, wild-type p53 colorectal cancer cells resist ferroptosis, while p53 mutations restore sensitivity, as shown by Xie et al

Materials and Methods Chemicals and Reagents 5-Fluorouracil (Cat# F6627), erastin (Cat# E7781) and ferrostatin-1 (Cat# SML0583) were purchased from Sigma-Aldrich (St

By wrapping the glutathione in this protective shell, we allow it to bypass the harsh digestive process

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Completing the link between exposure science and toxicology for improved environmental health decision making: the aggregate exposure pathway framework

Also, the upregulation of UCP2 increases the concentration in hypoxia-inducible factor 1-alpha (HIF-1), which reduces PPAR and favors lipid depots