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6, June 2008, pp

More studies should be conducted to investigate whether the observed increases in cytokines IFN-, TNF-, IL-2, and decrease in IL-10 found in granuloma supernatants is indeed the cause of the decreased burden of mycobacterial

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Notably, phosphorylation time-point experiments indicated that these effects are primary C5aR1-mediated responses, on which CXCL1/IL-8 acts later in time to further sustain these changes and make them chronic

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