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Jha et al., 2022) (Figure 2A)
Transgenic mice had increased levels of EAAT2 and reduced SNL-induced NP, and EAAT2 induction by ceftriaxone reduced SNL-induced NP in both mice, suggesting that overexpression of ET-1 suppressed NP by upregulating spinal EAAT2 expression via ET receptors [385]
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