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(R)-(+)-tert-Butylsulfinamide achieves stereoselective reactions by condensing with carbonyl groups to form sulfinyl imine intermediates, and after the reaction, this group can be removed under acidic conditions to obtain the target product

This finding provides a new and compelling mechanistic link between copper overload and neuronal loss in AD
The GSH-GPX4 pathway, the FSP1-CoQ10 pathway, the GCH1-BH4 pathway, the DHODH-CoQH2 system and the sex hormones suppress ferroptosis

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Despite the ubiquitous endogenous biosynthesis, specific medical conditions are associated with low circulating CoQ10 levels

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