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These overwhelm standard growth factors, as all are rapidly destroyed in human gastric juice within 15 min [72], are unable to be applied alone, and require the addition of various carriers or biological scaffolds or various combinations (for review, see [14])

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Dihexa (PNB-0408) is a synthetic oligopeptide derived from angiotensin IV, developed at Washington State University in the laboratory of Dr Joseph Harding
